Meet The Professors 2004 VOL 3, ISSUE 2

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Emens LA, Davidson NE. Adjuvant hormonal therapy for premenopausal women with breast cancer. Clin Cancer Res 2003;9(1 Pt 2):486S-94S. Abstract

Fisher B et al. A randomized clinical trial evaluating sequential methotrexate and fluorouracil in the treatment of patients with node-negative breast cancer who have estrogen-receptornegative tumors. N Engl J Med 1989;320(8):473-8. Abstract

Love RR et al. Her-2/neu overexpression and response to oophorectomy plus tamoxifen adjuvant therapy in estrogen receptor-positive premenopausal women with operable breast cancer. J Clin Oncol 2003;21(3):453-7. Abstract

Minton SE, Munster PN. Chemotherapy-induced amenorrhea and fertility in women undergoing adjuvant treatment for breast cancer. Cancer Control 2002;9(6):466-72. Abstract

Paik S et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004;351(27):2817-26. Abstract

Ravdin PM et al. Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer. J Clin Oncol 2001;19(4):980-91. Abstract

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Editor's Note:
Til death do us part

CASE 1: A 36-year-old woman with a family history of breast cancer and a poorly differentiated, node-negative IDC of the breast who wishes to retain her fertility (from the practice of Dr Richard S Zelkowitz)

- Select publications

Case 2: A 48-year-old woman with an ER/PR-negative, HER2-positive invasive ductal carcinoma with 11/16 positive nodes who developed CNS and bone metastases three years after local and adjuvant systemic therapy (from the practice of Dr Leonard J Seigel)

- Select publications

Case 3: A 73-year-old woman with ER/PR-positive, node-positive breast cancer who was switched to exemestane after three years of adjuvant tamoxifen (from the practice of Dr Arnold S Blaustein)

- Select publications

Case 4: A woman in her late forties diagnosed with a small, node-negative breast tumor who developed a sternal metastasis after two and one half years of tamoxifen with a shift in tumor phenotype from the primary lesion (from the practice of Dr Lowell L Hart)

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Case 5: A 67-year-old woman a large ER/PR-positive, HER2-negative infiltrating ductal carcinoma with two positive lymph nodes (from the practice of Dr Lawrence A Tepper)

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Case 6: A 41-year-old woman with an ER/PR-positive, HER2-negative breast tumor who had significant residual disease after AC and docetaxel neoadjuvant therapy (from the practice of Dr Michael S Wertheim)

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Case 7: A 72-year-old woman with high-risk, ER/PR-positive breast cancer who refuses treatment with AIs after experiencing uncommon side effects and who subsequently develops a painful metastatic skin nodule and bone metastases (from the practice of Dr David M Dresdner)

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